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Lyme Disease Lyme Arthritis ~~~~~~~~~~~~~~ Lyme disease is a tick-transmitted inflammatory disorder characterized by an early focal skin lesion, and subsequently a growing red area on the skin (erythema chronicum migrans or ECM). The disorder may be followed weeks later by neurological, heart or joint abnormalities. Symptomatology ~~~~~~~~~~~~~~ The first symptom of Lyme disease is a skin lesion. Known as erythema chronicum migrans, or ECM, this usually begins as a red discoloration (macule) or as an elevated …

…patients who have not yet developed the antibodies. This would enable doctors to diagnose Lyme disease very early in the course of the illness. This disease entry is based upon medical information available through July 1989. Since NORD's resources are limited, it is not possible to keep every entry in the Rare Disease Database completely current and accurate. Please check with the agencies listed in the Resources section for the most current information about this disorder.